Reticulocyte hemoglobin content as an early predictive biomarker of brain iron deficiency
نویسندگان
چکیده
منابع مشابه
Diagnosis of Iron Deficiency and Iron Deficiency Anemia with Reticulocyte Hemoglobin Content among Children Aged 6-18 Years
Background: Iron deficiency (ID) is the most common micronutrient deficiency in the world. If left untreated, ID will lead to iron deficiency anemia (IDA) and other irreversible consequences. The American Academy of Pediatrics recommended reticulocyte hemoglobin content (Ret-He) as an alternative laboratory examination to screen and detect ID. We aimed to compare Ret-He with other laboratory pa...
متن کاملReticulocyte hemoglobin content to diagnose iron deficiency in children.
CONTEXT Early identification of iron deficiency in children is essential to prevent the damaging long-term consequences of this disease. However, it is not clear which indices should be included in a diagnostic panel for iron deficiency and iron deficiency anemia in children. OBJECTIVE To develop an effective approach for the diagnosis of iron deficiency and iron deficiency anemia in young ch...
متن کاملScreening healthy infants for iron deficiency using reticulocyte hemoglobin content.
CONTEXT Current clinical practice relies on hemoglobin to detect iron deficiency, which misses infants not yet anemic and places them at higher risk for neurocognitive impairment. Reticulocyte hemoglobin content (CHr) has never been compared with hemoglobin for screening healthy infants. OBJECTIVES To evaluate CHr for detecting iron deficiency without anemia in healthy 9- to 12-month-old infa...
متن کاملClinical utility of the reticulocyte hemoglobin content in the diagnosis of iron deficiency.
Determination of the reticulocyte hemoglobin content (CHr) provides an early measure of functional iron deficiency because reticulocytes are the earliest erythrocytes released into blood and circulate for only 1 to 2 days. The CHr in 78 patients undergoing bone marrow examination was measured to assess its clinical utility for the diagnosis of iron deficiency. Twenty-eight patients were iron de...
متن کاملClinical Significance of Reticulocyte Hemoglobin Content in the Diagnosis of Iron Deficiency Anemia
OBJECTIVE The aim of this study was to evaluate the clinical significance of reticulocyte hemoglobin content (CHr) in the diagnosis of iron deficiency anemia (IDA) and to compare it with other conventional iron parameters. MATERIALS AND METHODS A total of 32 female patients with IDA (serum hemoglobin <120 g/L and serum ferritin <20 ng/ mL) and 18 female patients with iron deficiency (serum he...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 2018
ISSN: 0031-3998,1530-0447
DOI: 10.1038/s41390-018-0178-6